Protein target identification and toxicological mechanism investigation of silver nanoparticles-induced hepatotoxicity by integrating proteomic and metallomic strategies

Protein target identification and toxicological mechanism investigation of silver nanoparticles-induced hepatotoxicity by integrating proteomic and metallomic strategies

Abstract Background Silver nanoparticles (AgNPs), as promising anti-microbials and anti-cancer therapeutics, the toxicological effect and killing efficiency towards cells need in-depth investigation for better applications in daily life and healthcare fields. Thus far, limited studies have yet eluci...

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Bibliographic Details
Main Authors: Ming Xu, Qiuyuan Yang, Lining Xu, Ziyu Rao, Dong Cao, Ming Gao, Sijin Liu
Format: Article
Language:English
Published: BMC 2019-11-01
Series:Particle and Fibre Toxicology
Subjects:
Silver nanoparticles
Silver ion
Hepatotoxicity
Protein target
Glutathione S-transferase
Online Access:http://link.springer.com/article/10.1186/s12989-019-0322-4

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http://link.springer.com/article/10.1186/s12989-019-0322-4

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