Functional amyloid signaling via the inflammasome, necrosome, and signalosome: New therapeutic targets in heart failure

As the most common cause of death and disability globally, heart disease remains an incompletely understood enigma. A growing number of cardiac diseases are being characterized by the presence of misfolded proteins underlying their pathophysiology, including cardiac amyloidosis and dilated cardiomyo...

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Bibliographic Details
Main Authors: Traci L Parry, Jason H Melehani, Mark J Ranek, Monte S Willis
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-05-01
Series:Frontiers in Cardiovascular Medicine
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fcvm.2015.00025/full