The Prognostic Relevance of the Proliferation Markers Ki-67 and Plk1 in Early-Stage Ovarian Cancer Patients With Serous, Low-Grade Carcinoma Based on mRNA and Protein Expression

The Prognostic Relevance of the Proliferation Markers Ki-67 and Plk1 in Early-Stage Ovarian Cancer Patients With Serous, Low-Grade Carcinoma Based on mRNA and Protein Expression

Since type and duration of an appropriate adjuvant chemotherapy in early-stage ovarian cancer (OC) are still being debated, novel markers for a better stratification of these patients are of utmost importance for the design of an improved chemotherapeutical strategy. In contrast to numerous cancer s...

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Bibliographic Details
Main Authors: Franz Rödel, Shengtao Zhou, Balász Győrffy, Monika Raab, Mourad Sanhaji, Ranadip Mandal, Daniel Martin, Sven Becker, Klaus Strebhardt
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-10-01
Series:Frontiers in Oncology
Subjects:
polo-like kinase 1
Ki-67/MIB1
ovarian cancer
prognosis
mRNA and protein expression
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.558932/full

Internet

https://www.frontiersin.org/article/10.3389/fonc.2020.558932/full

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