6-Hydroxy-4-(pyridin-3-yl)-5-(2-thienylcarbonyl)-6-trifluoromethyl-3,4,5,6-tetrahydropyrimidin-2(1H)-one
In the title compound, C15H12F3N3O3S, the pyrimidine ring adopts a half-chair conformation with the mean plane formed by the ring atoms excluding the C atom bonded to thiophene-2-carbonyl group lying nearly perpendicular to the pyridine and thiophene rings, making dihedral angles of 84.91&#8...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
International Union of Crystallography
2010-11-01
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| Series: | Acta Crystallographica Section E |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S1600536810041085 |
| Summary: | In the title compound, C15H12F3N3O3S, the pyrimidine ring adopts a half-chair conformation with the mean plane formed by the ring atoms excluding the C atom bonded to thiophene-2-carbonyl group lying nearly perpendicular to the pyridine and thiophene rings, making dihedral angles of 84.91 (4) and 87.40 (5)°, respectively. The dihedral angle between the pyridine and thiophene rings is 54.44 (5)°. The crystal structure is stabilized by intermolecular O—H...O and N—H...N hydrogen bonds and weak C—H...O interactions further consolidate the structure. |
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| ISSN: | 1600-5368 |