Protective Role of Myeloid Cells Expressing a G-CSF Receptor Polymorphism in an Induced Model of Lupus

Protective Role of Myeloid Cells Expressing a G-CSF Receptor Polymorphism in an Induced Model of Lupus

The genetic analysis of the lupus-prone NZM2410 mouse has identified a suppressor locus, Sle2c2, which confers resistance to spontaneous lupus in combination with NZM2410 susceptibility loci, or in the chronic graft-versus-host disease (cGVHD) induced model of lupus in the B6.Sle2c2 congenic strain....

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Bibliographic Details
Main Authors:	Ramya Sivakumar, Georges Abboud, Clayton E. Mathews, Mark A. Atkinson, Laurence Morel
Format:	Article
Language:	English
Published:	Frontiers Media S.A. 2018-05-01
Series:	Frontiers in Immunology
Subjects:	G-CSF-R lupus neutrophils tolerogenic dendritic cells suppressive allele
Online Access:	http://journal.frontiersin.org/article/10.3389/fimmu.2018.01053/full

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