Exposure to Iron Oxide Nanoparticles Coated with Phospholipid-Based Polymeric Micelles Induces Biochemical and Histopathological Pulmonary Changes in Mice

Exposure to Iron Oxide Nanoparticles Coated with Phospholipid-Based Polymeric Micelles Induces Biochemical and Histopathological Pulmonary Changes in Mice

The biochemical and histopathological changes induced by the exposure to iron oxide nanoparticles coated with phospholipid-based polymeric micelles (IONPs-PM) in CD-1 mice lungs were analyzed. After 2, 3, 7 and 14 days following the intravenous injection of IONPs-PM (5 and 15 mg Fe/kg bw), lactate d...

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Bibliographic Details
Main Authors: Mihaela Radu (Balas), Ioana Mihaela Din (Popescu), Anca Hermenean, Otilia Ludmila Cinteză, Radu Burlacu, Aurel Ardelean, Anca Dinischiotu
Format: Article
Language:English
Published: MDPI AG 2015-12-01
Series:International Journal of Molecular Sciences
Subjects:
phospholipid micelles-coated iron oxide nanoparticles
oxidative stress
apoptotic markers
histopathological alterations
Online Access:http://www.mdpi.com/1422-0067/16/12/26173

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