Unbiased and automated identification of a circulating tumour cell definition that associates with overall survival.

Circulating tumour cells (CTC) in patients with metastatic carcinomas are associated with poor survival and can be used to guide therapy. Classification of CTC however remains subjective, as they are morphologically heterogeneous. We acquired digital images, using the CellSearch™ system, from blood...

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Bibliographic Details
Main Authors: Sjoerd T Ligthart, Frank A W Coumans, Gerhardt Attard, Amy Mulick Cassidy, Johann S de Bono, Leon W M M Terstappen
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3210171?pdf=render