| Summary: | Background: Gastric leiomyomas are usually solitary, rounded, and demarcated masses, and multiple leiomyomas (more than three) are extremely rare. We report a case of a 30-year-old woman who was referred to our hospital for further treatment of an enlarging gastric submucosal tumour (SMT).Case Presentation: She underwent laparoscopic gastric partial resection with oesophagogastroduodenoscopy (OGD), which revealed a multinodular gastric SMT (10 cm in diameter) located in the upper body of the stomach. Endoscopic ultrasonography (EUS) revealed a hypoechoic mass located in the fourth layer and multiple nodules approximately 1 cm in diameter. We subsequently performed EUS-guided fine-needle aspiration biopsy. The patient underwent laparoscopic gastric partial resection with EGD. Because the tumour was extensive on the lesser curvature of the stomach and was located near the oesophagogastric junction, we preserved the gastric function with minimal resection of the stomach. No intraoperative or postoperative complications were observed. The tumour was pathologically diagnosed as gastric leiomyoma. Laparoscopic minimized resection used by endoscope, can avoid gastric deformity and preserve gastric function, especially when the gastric SMTs are located near the oesophagogastric junction.Conclusion: Laparoscopic gastric partial resection with EGD is an effective treatment option for complete resection of extensive gastric SMT.
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