Exploring leptin antagonism in ophthalmic cell models.

BACKGROUND:Emerging evidence suggests that angiogenic and pro-inflammatory cytokine leptin might be implicated in ocular neovascularization. However, the potential of inhibiting leptin function in ophthalmic cells has never been explored. Here we assessed mitogenic, angiogenic, and signaling leptin...

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Bibliographic Details
Main Authors: Laura Scolaro, Cristina Parrino, Roberta Coroniti, Laszlo Otvos, Eva Surmacz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3789671?pdf=render