Biochemical profiling of areca nut product Dohra

• Main Authors: Ravi Mehrotra, Amrita Nandan, Vishwas Sharma, Anshika Chandra, Ravi Kaushik
• Format: Article
• Language: English
• Published: European Publishing 2018-10-01
• Series: Tobacco Induced Diseases
• Subjects: biochemical profiling; areca nut product; Dohra
• Online Access: http://www.journalssystem.com/tid/,95191,0,2.html

Introduction Dohra is a locally produced areca nut preparations used with or without tobacco in Allahabad, Jaunpur and Pratapgarh districts of Uttar Pradesh (UP), India. Different varieties of Dohra exist such as Sukha Dohra, Geela Dohra, etc. Evidence suggests that it causes Oral Potentially Malignant Disorders and Oral Cancer. It contains arecoline which is a well-known carcinogen. In order to understand the potential role of Dohra in causing cancer biochemical profiling of different varieties of Dohra is needed. Aim To describe the biochemical profile of different varieties of Dohra. Methods Different varieties of Dohra were collected from Allahabad, Jaunpur and Pratapgarh districts of UP. All the varieties of Dohra were analyzed for biochemical profiling through Continuous Flow Autoanalyzer (CFA) using Flow View Solution 3700 Analyzer (version 1.2.2) software. Results The biochemical changes at arecoline levels were observed in different varieties of Dohra. The detailed chemical profiling will be furnished in the meeting. Conclusions Different varieties of Dohra preparations are produced and each of them have a different biochemical profile. The Dohra is rich is arecoline and hence its use should be banned/avoided.