Regulatory T cells in tumor microenvironment: new mechanisms, potential therapeutic strategies and future prospects
Abstract Regulatory T cells (Tregs) characterized by the expression of the master transcription factor forkhead box protein p3 (Foxp3) suppress anticancer immunity, thereby hindering protective immunosurveillance of tumours and hampering effective antitumour immune responses in tumour-bearing hosts,...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
BMC
2020-07-01
|
| Series: | Molecular Cancer |
| Online Access: | http://link.springer.com/article/10.1186/s12943-020-01234-1 |