The nucleosome DNA entry-exit site is important for transcription termination and prevention of pervasive transcription

The nucleosome DNA entry-exit site is important for transcription termination and prevention of pervasive transcription

Compared to other stages in the RNA polymerase II transcription cycle, the role of chromatin in transcription termination is poorly understood. We performed a genetic screen in Saccharomyces cerevisiae to identify histone mutants that exhibit transcriptional readthrough of terminators. Amino acid su...

Full description

Bibliographic Details
Main Authors: A Elizabeth Hildreth, Mitchell A Ellison, Alex M Francette, Julia M Seraly, Lauren M Lotka, Karen M Arndt
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2020-08-01
Series:eLife
Subjects:
DNA entry-exit site
nucleosome
RNA polymerase II
transcription termination
noncoding RNA
chromatin
Online Access:https://elifesciences.org/articles/57757

Similar Items

Similar Items