MicroRNA-221 promotes cell proliferation, migration, and differentiation by regulation of ZFPM2 in osteoblasts

MicroRNA-221 promotes cell proliferation, migration, and differentiation by regulation of ZFPM2 in osteoblasts

Bone fracture is a common medical condition, which may occur due to traumatic injury or disease-related conditions. Evidence suggests that microRNAs (miRNAs) can regulate osteoblast differentiation and function. In this study, we explored the effects and mechanism of miR-221 on the growth and migrat...

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Bibliographic Details
Main Authors: Xingguo Zheng, Jinhua Dai, Haijun Zhang, Zhibin Ge
Format: Article
Language:English
Published: Associação Brasileira de Divulgação Científica 2018-10-01
Series:Brazilian Journal of Medical and Biological Research
Subjects:
MicroRNA-221
Bone fracture
Osteoblast differentiation
ZFPM2
Wnt/Notch
Smad
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2018001200602&lng=en&tlng=en

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