The challenges in data integration – heterogeneity and complexity in clinical trials and patient registries of Systemic Lupus Erythematosus

The challenges in data integration – heterogeneity and complexity in clinical trials and patient registries of Systemic Lupus Erythematosus

Abstract Background Individual clinical trials and cohort studies are a useful source of data, often under-utilised once a study has ended. Pooling data from multiple sources could increase sample sizes and allow for further investigation of treatment effects; even if the original trial did not meet...

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Bibliographic Details
Main Authors: Helen Le Sueur, Ian N. Bruce, Nophar Geifman, on behalf of the MASTERPLANS Consortium
Format: Article
Language:English
Published: BMC 2020-06-01
Series:BMC Medical Research Methodology
Subjects:
Data integration
Data harmonisation
Clinical trials
Lupus
Pooled analysis
Online Access:http://link.springer.com/article/10.1186/s12874-020-01057-0

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