Optimal pulse length of insonification for Piezo1 activation and intracellular calcium response

Abstract Ultrasound (US) neuromodulation, especially sonogenetics, has been demonstrated with potential applications in noninvasive and targeted treatment of various neurological disorders. Despite the growing interest, the mechanism for US neuromodulation remains elusive, and the optimal condition...

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Bibliographic Details
Main Authors: Defei Liao, Ming-Yen Hsiao, Gaoming Xiang, Pei Zhong
Format: Article
Language:English
Published: Nature Publishing Group 2021-01-01
Series:Scientific Reports
Online Access:https://doi.org/10.1038/s41598-020-78553-2