Phenotype, Function, and Mobilization of 6-Sulfo LacNAc-Expressing Monocytes in Atopic Dermatitis

Phenotype, Function, and Mobilization of 6-Sulfo LacNAc-Expressing Monocytes in Atopic Dermatitis

Mononuclear phagocytes (MPs) are important immune regulatory cells in atopic dermatitis (AD). We previously identified 6-sulfo LacNAc-expressing monocytes (slanMo) as TNF-α- and IL-23-producing cells in psoriatic skin lesions and as inducers of IFN-γ-, IL-17-, and IL-22-producing T cells. These cyto...

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Bibliographic Details
Main Authors: Wojciech Baran, Stephanie Oehrl, Fareed Ahmad, Thomas Döbel, Christina Alt, Angelika Buske-Kirschbaum, Marc Schmitz, Knut Schäkel
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-06-01
Series:Frontiers in Immunology
Subjects:
atopic dermatitis
dendritic cells
6-sulfo LacNAc-expressing monocytes
immunology
inflammation
IL-12
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.01352/full

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