A novel environment-evoked transcriptional signature predicts reactivity in single dentate granule neurons
Single nuclei RNA-seq has been used to characterize transcriptional signature of environment-related activity in cells of the dentate gyrus. Here the authors use this approach to show that whether a neuron will be reactivated in response to re-exposure to a previous environment can be predicted by i...
Main Authors: | Baptiste N. Jaeger, Sara B. Linker, Sarah L. Parylak, Jerika J. Barron, Iryna S. Gallina, Christian D. Saavedra, Conor Fitzpatrick, Christina K. Lim, Simon T. Schafer, Benjamin Lacar, Sebastian Jessberger, Fred H. Gage |
---|---|
Format: | Article |
Language: | English |
Published: |
Nature Publishing Group
2018-08-01
|
Series: | Nature Communications |
Online Access: | https://doi.org/10.1038/s41467-018-05418-8 |
Similar Items
-
Nuclear RNA-seq of single neurons reveals molecular signatures of activation
by: Benjamin Lacar, et al.
Published: (2016-04-01) -
The effect of immature adult-born dentate granule cells on hyponeophagial behavior is related to their roles in learning and memory
by: Wei eDeng, et al.
Published: (2015-03-01) -
Correction: Corrigendum: Nuclear RNA-seq of single neurons reveals molecular signatures of activation
by: Benjamin Lacar, et al.
Published: (2016-06-01) -
Correction: Corrigendum: Nuclear RNA-seq of single neurons reveals molecular signatures of activation
by: Benjamin Lacar, et al.
Published: (2017-03-01) -
Selection of distinct populations of dentate granule cells in response to inputs as a mechanism for pattern separation in mice
by: Wei Deng, et al.
Published: (2013-03-01)