Prenatal Maternal Lipopolysaccharide and Mild Newborn Hyperoxia Increase Intrapulmonary Airway but Not Vessel Reactivity in a Mouse Model

Prenatal Maternal Lipopolysaccharide and Mild Newborn Hyperoxia Increase Intrapulmonary Airway but Not Vessel Reactivity in a Mouse Model

Maternal infection is a risk for preterm delivery. Preterm newborns often require supplemental oxygen to treat neonatal respiratory distress. Newborn hyperoxia exposure is associated with airway and vascular hyperreactivity, while the complications of maternal infection are variable. In a mouse mode...

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Bibliographic Details
Main Authors: Margaret E. Kuper-Sassé, Peter M. MacFarlane, Catherine A. Mayer, Richard J. Martin, Y. S. Prakash, Christina M. Pabelick, Thomas M. Raffay
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Children
Subjects:
airway hyperreactivity
vessel hyperreactivity
inflammation
hyperoxia
precision-cut lung slice
Online Access:https://www.mdpi.com/2227-9067/8/3/195

Internet

https://www.mdpi.com/2227-9067/8/3/195

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