Perturbation of IIS/TOR signaling alters the landscape of sex-differential gene expression in Drosophila

Perturbation of IIS/TOR signaling alters the landscape of sex-differential gene expression in Drosophila

Abstract Background The core functions of the insulin/insulin-like signaling and target of rapamycin (IIS/TOR) pathway are nutrient sensing, energy homeostasis, growth, and regulation of stress responses. This pathway is also known to interact directly and indirectly with the sex determination regul...

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Bibliographic Details
Main Authors: Rita M. Graze, Ruei-Ying Tzeng, Tiffany S. Howard, Michelle N. Arbeitman
Format: Article
Language:English
Published: BMC 2018-12-01
Series:BMC Genomics
Subjects:
Drosophila
Sexual dimorphism
Insulin signaling
Gene expression
Sex bias
RNA-seq
Online Access:http://link.springer.com/article/10.1186/s12864-018-5308-3

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