Hemorheological parameters in patients with arterial hypertension and lipid metabolism disorders
Aim. To study hemorheological disturbances in patients with essential arterial hypertension (AH) and dyslipidemia (DLP). Material and methods. In total, 83 AH patients without target organ disease were examined, including 30 without lipid metabolism disorders and 53 with DLP (total cholesterol, TCH...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | Russian |
| Published: |
«SILICEA-POLIGRAF» LLC
2010-02-01
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| Series: | Кардиоваскулярная терапия и профилактика |
| Subjects: | |
| Online Access: | https://cardiovascular.elpub.ru/jour/article/view/2009 |
| Summary: | Aim. To study hemorheological disturbances in patients with essential arterial hypertension (AH) and dyslipidemia (DLP). Material and methods. In total, 83 AH patients without target organ disease were examined, including 30 without lipid metabolism disorders and 53 with DLP (total cholesterol, TCH >5 mmol/l and/or triglycerides, TG >1,7 mmol/l). All participants underwent general clinical examination and hemorheology assessment (hematocrit, plasma viscosity, blood viscosity by rotation viscosimetry at various shift speeds, erythrocyte aggregation (EA) by optic and automatic methods, erythrocyte deformability (ED) by filtration method, and erythrocyte cytoarchitectonics). Results. In patients with AH and DLP, comparing to healthy participants, impaired blood rheology was observed, manifesting in increased blood viscosity in high and average shift speeds, increased EA and impaired ED, which correlated with lipid metabolism disturbances. Conclusion. In patients with AH and DLP, blood rheology parameters were significantly affected due to disturbed lipid metabolism. |
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| ISSN: | 1728-8800 2619-0125 |