Beclin‐1 improves mitochondria‐associated membranes in the heart during endotoxemia

Beclin‐1 improves mitochondria‐associated membranes in the heart during endotoxemia

Abstract Mitochondria‐associated membranes (MAMs) are essential to mitochondria. This study was to determine whether endotoxemia rearranges MAMs in the heart, and whether Beclin‐1 regulates this process. Wild‐type mice and mice with a cardiac‐specific overexpression of Beclin‐1 (Becn1‐Tg), or a hete...

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Bibliographic Details
Main Authors: Yuxiao Sun, Ying Cai, Suhong Qian, Hellen Chiou, Qun S. Zang
Format: Article
Language:English
Published: Wiley 2021-03-01
Series:FASEB BioAdvances
Subjects:
beclin‐1
cardiac dysfunction
LPS
MAMs
sepsis
Online Access:https://doi.org/10.1096/fba.2020-00039

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