High-Density Dielectrophoretic Microwell Array for Detection, Capture, and Single-Cell Analysis of Rare Tumor Cells in Peripheral Blood.

High-Density Dielectrophoretic Microwell Array for Detection, Capture, and Single-Cell Analysis of Rare Tumor Cells in Peripheral Blood.

Development of a reliable platform and workflow to detect and capture a small number of mutation-bearing circulating tumor cells (CTCs) from a blood sample is necessary for the development of noninvasive cancer diagnosis. In this preclinical study, we aimed to develop a capture system for molecular...

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Main Authors: Atsushi Morimoto, Toshifumi Mogami, Masaru Watanabe, Kazuki Iijima, Yasuyuki Akiyama, Koji Katayama, Toru Futami, Nobuyuki Yamamoto, Takeshi Sawada, Fumiaki Koizumi, Yasuhiro Koh
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4480363?pdf=render

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