One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines

One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines

Novel 1H-pyrimido [4,5-c][1,2]diazepines 3 & 4 and pyrazolo [3,4-d]pyrimidines 6 were regioselectively synthesised by the reaction of 1,3-dimethyl-6-hydrazinouracils 1 with various α,β-unsaturated compounds 2 and α-ketoalkynes 8 in excellent yields.

Bibliographic Details
Main Authors: Dipak Prajapati, Partha P. Baruah, Baikuntha J. Gogoi, Jagir S. Sandhu
Format: Article
Language:English
Published: Beilstein-Institut 2006-03-01
Series:Beilstein Journal of Organic Chemistry
Online Access:https://doi.org/10.1186/1860-5397-2-5
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spelling doaj-937448c6a5db420ca55b05e550078ea32021-02-02T01:38:28ZengBeilstein-InstitutBeilstein Journal of Organic Chemistry1860-53972006-03-0121510.1186/1860-5397-2-51860-5397-2-5One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidinesDipak Prajapati0Partha P. Baruah1Baikuntha J. Gogoi2Jagir S. Sandhu3Department of Medicinal Chemistry, Regional Research Laboratory, Jorhat 785006, Assam, IndiaDepartment of Medicinal Chemistry, Regional Research Laboratory, Jorhat 785006, Assam, IndiaDepartment of Medicinal Chemistry, Regional Research Laboratory, Jorhat 785006, Assam, IndiaDepartment of Chemistry, Panjabi University, Patiala 147 002, Punjab, IndiaNovel 1H-pyrimido [4,5-c][1,2]diazepines 3 & 4 and pyrazolo [3,4-d]pyrimidines 6 were regioselectively synthesised by the reaction of 1,3-dimethyl-6-hydrazinouracils 1 with various α,β-unsaturated compounds 2 and α-ketoalkynes 8 in excellent yields.https://doi.org/10.1186/1860-5397-2-5
collection DOAJ
language English
format Article
sources DOAJ
author Dipak Prajapati
Partha P. Baruah
Baikuntha J. Gogoi
Jagir S. Sandhu
spellingShingle Dipak Prajapati
Partha P. Baruah
Baikuntha J. Gogoi
Jagir S. Sandhu
One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines
Beilstein Journal of Organic Chemistry
author_facet Dipak Prajapati
Partha P. Baruah
Baikuntha J. Gogoi
Jagir S. Sandhu
author_sort Dipak Prajapati
title One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines
title_short One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines
title_full One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines
title_fullStr One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines
title_full_unstemmed One-pot synthesis of novel 1H-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines
title_sort one-pot synthesis of novel 1h-pyrimido[4,5-c][1,2]diazepines and pyrazolo[3,4-d]pyrimidines
publisher Beilstein-Institut
series Beilstein Journal of Organic Chemistry
issn 1860-5397
publishDate 2006-03-01
description Novel 1H-pyrimido [4,5-c][1,2]diazepines 3 & 4 and pyrazolo [3,4-d]pyrimidines 6 were regioselectively synthesised by the reaction of 1,3-dimethyl-6-hydrazinouracils 1 with various α,β-unsaturated compounds 2 and α-ketoalkynes 8 in excellent yields.
url https://doi.org/10.1186/1860-5397-2-5
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AT baikunthajgogoi onepotsynthesisofnovel1hpyrimido45c12diazepinesandpyrazolo34dpyrimidines
AT jagirssandhu onepotsynthesisofnovel1hpyrimido45c12diazepinesandpyrazolo34dpyrimidines
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