Necessity of Epigenetic Epidemiology Studies on the Carcinogenesis of Lung Cancer in Never Smokers

Necessity of Epigenetic Epidemiology Studies on the Carcinogenesis of Lung Cancer in Never Smokers

Based on epidemiological and genomic characteristics, lung cancer in never smokers (LCNS) is a different disease from lung cancer in smokers. Based on current research, the main risk factor for LCNS may be air pollution. A recent case-control study in Koreans reported that nitrogen dioxide (NO2) may...

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Main Author: Jong-Myon Bae
Format: Article
Language:English
Published: Korean Society for Preventive Medicine 2018-09-01
Series:Journal of Preventive Medicine and Public Health
Subjects:
Air pollution
Gene-environment interaction
Epigenetics
Epidemiology
Online Access:http://www.jpmph.org/upload/pdf/jpmph-51-5-263.pdf
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spelling doaj-93703f6fea294bed8c17442b81a1ab4d2020-11-24T21:48:37ZengKorean Society for Preventive MedicineJournal of Preventive Medicine and Public Health1975-83752233-45212018-09-0151526326410.3961/jpmph.18.0761986Necessity of Epigenetic Epidemiology Studies on the Carcinogenesis of Lung Cancer in Never SmokersJong-Myon BaeBased on epidemiological and genomic characteristics, lung cancer in never smokers (LCNS) is a different disease from lung cancer in smokers. Based on current research, the main risk factor for LCNS may be air pollution. A recent case-control study in Koreans reported that nitrogen dioxide (NO2) may be a risk factor for LCNS. Additionally, a cohort study showed that exposure to NO2 was associated with significant hypomethylation. Thus, epigenetic epidemiology studies are needed in the near future to evaluate the carcinogenesis of LCNS according to chronic exposure to air pollution and/or viral infections.http://www.jpmph.org/upload/pdf/jpmph-51-5-263.pdfAir pollutionGene-environment interactionEpigeneticsEpidemiology
collection DOAJ
language English
format Article
sources DOAJ
author Jong-Myon Bae
spellingShingle Jong-Myon Bae
Necessity of Epigenetic Epidemiology Studies on the Carcinogenesis of Lung Cancer in Never Smokers
Journal of Preventive Medicine and Public Health
Air pollution
Gene-environment interaction
Epigenetics
Epidemiology
author_facet Jong-Myon Bae
author_sort Jong-Myon Bae
title Necessity of Epigenetic Epidemiology Studies on the Carcinogenesis of Lung Cancer in Never Smokers
title_short Necessity of Epigenetic Epidemiology Studies on the Carcinogenesis of Lung Cancer in Never Smokers
title_full Necessity of Epigenetic Epidemiology Studies on the Carcinogenesis of Lung Cancer in Never Smokers
title_fullStr Necessity of Epigenetic Epidemiology Studies on the Carcinogenesis of Lung Cancer in Never Smokers
title_full_unstemmed Necessity of Epigenetic Epidemiology Studies on the Carcinogenesis of Lung Cancer in Never Smokers
title_sort necessity of epigenetic epidemiology studies on the carcinogenesis of lung cancer in never smokers
publisher Korean Society for Preventive Medicine
series Journal of Preventive Medicine and Public Health
issn 1975-8375
2233-4521
publishDate 2018-09-01
description Based on epidemiological and genomic characteristics, lung cancer in never smokers (LCNS) is a different disease from lung cancer in smokers. Based on current research, the main risk factor for LCNS may be air pollution. A recent case-control study in Koreans reported that nitrogen dioxide (NO2) may be a risk factor for LCNS. Additionally, a cohort study showed that exposure to NO2 was associated with significant hypomethylation. Thus, epigenetic epidemiology studies are needed in the near future to evaluate the carcinogenesis of LCNS according to chronic exposure to air pollution and/or viral infections.
topic Air pollution
Gene-environment interaction
Epigenetics
Epidemiology
url http://www.jpmph.org/upload/pdf/jpmph-51-5-263.pdf
work_keys_str_mv AT jongmyonbae necessityofepigeneticepidemiologystudiesonthecarcinogenesisoflungcancerinneversmokers
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