The Axenfeld–Rieger Syndrome Gene <i>FOXC1</i> Contributes to Left–Right Patterning

The Axenfeld–Rieger Syndrome Gene <i>FOXC1</i> Contributes to Left–Right Patterning

Precise spatiotemporal expression of the <i>Nodal</i>-<i>Lefty</i>-<i>Pitx2</i> cascade in the lateral plate mesoderm establishes the left–right axis, which provides vital cues for correct organ formation and function. Mutations of one cascade constituent <i>...

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Bibliographic Details
Main Authors: Paul W. Chrystal, Curtis R. French, Francesca Jean, Serhiy Havrylov, Suey van Baarle, Ann-Marie Peturson, Pengfei Xu, J. Gage Crump, David B. Pilgrim, Ordan J. Lehmann, Andrew J. Waskiewicz
Format: Article
Language:English
Published: MDPI AG 2021-01-01
Series:Genes
Subjects:
<i>FOXC1</i>
Axenfeld–Rieger syndrome
left–right patterning
zebrafish
<i>LEFTY</i>
Online Access:https://www.mdpi.com/2073-4425/12/2/170

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