The role of Peyer´s patches in synchronizing gut IgA responses

Because Peyer’s patches (PP) are the main inductive sites for gut IgA responses we have focused this review on what we know about the function of PP germinal center (GC). The vast majority of IgA gene sequences in the gut lamina propria (LP) are heavily mutated arguing for an origin in GC. Because P...

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Bibliographic Details
Main Authors: Nils Yngve Lycke, Mats eBemark
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Immunology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fimmu.2012.00329/full