Peripherally administered nanoparticles target monocytic myeloid cells, secondary lymphoid organs and tumors in mice.

Nanoparticles have been extensively developed for therapeutic and diagnostic applications. While the focus of nanoparticle trafficking in vivo has traditionally been on drug delivery and organ-level biodistribution and clearance, recent work in cancer biology and infectious disease suggests that tar...

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Bibliographic Details
Main Authors: Iraklis C Kourtis, Sachiko Hirosue, Alexandre de Titta, Stephan Kontos, Toon Stegmann, Jeffrey A Hubbell, Melody A Swartz
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/23626707/pdf/?tool=EBI