Prophylactic Administration of Nanocurcumin Abates the Incidence of Liver Toxicity Induced by an Overdose of Copper Sulfate: Role of CYP4502E1, NF-κB and Bax Expressions

Background: The consequences of excess copper in human tissue are the alterations in the oxidative stress markers and peroxidative damage of membrane lipids. Unselective copper binding may be the clue to damaging impact to protein construction and hence modifying their biological functions. The aim...

Full description

Bibliographic Details
Main Authors: Ahlam Alhusaini, Iman H. Hasan, Nouf Aldowsari, Njood Alsaadan
Format: Article
Language:English
Published: SAGE Publishing 2018-12-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/1559325818816284