Fetal Programming by Methyl Donors Modulates Central Inflammation and Prevents Food Addiction-Like Behavior in Rats

Fetal Programming by Methyl Donors Modulates Central Inflammation and Prevents Food Addiction-Like Behavior in Rats

Fetal programming by hypercaloric intake leads to food addiction-like behavior and brain pro-inflammatory gene expression in offspring. The role of methylome modulation during programming on central immune activation and addiction-like behavior has not been characterized. We employed a nutritional p...

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Bibliographic Details
Main Authors: Gabriela Cruz-Carrillo, Larisa Montalvo-Martínez, Marcela Cárdenas-Tueme, Sofia Bernal-Vega, Roger Maldonado-Ruiz, Diana Reséndez-Pérez, Dalia Rodríguez-Ríos, Gertrud Lund, Lourdes Garza-Ocañas, Alberto Camacho-Morales
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Neuroscience
Subjects:
programming
methylome
addiction
nucleus accumbens
inflammation
Online Access:https://www.frontiersin.org/article/10.3389/fnins.2020.00452/full

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