Epigenetic Consequences of in Utero Exposure to Rosuvastatin: Alteration of Histone Methylation Patterns in Newborn Rat Brains

Epigenetic Consequences of in Utero Exposure to Rosuvastatin: Alteration of Histone Methylation Patterns in Newborn Rat Brains

Rosuvastatin (RST) is primarily used to treat high cholesterol levels. As it has potentially harmful but not well-documented effects on embryos, RST is contraindicated during pregnancy. To demonstrate whether RST could induce molecular epigenetic events in the brains of newborn rats, pregnant mother...

Full description

Bibliographic Details
Main Authors: Karolina Dulka, Melinda Szabo, Noémi Lajkó, István Belecz, Zsófia Hoyk, Karoly Gulya
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:International Journal of Molecular Sciences
Subjects:
epigenetics
H3K4me1
H3K4me3
histone methylation
immunohistochemistry
in utero
Online Access:https://www.mdpi.com/1422-0067/22/7/3412

Similar Items

Similar Items