6-Methylideneandrost-4-ene-3,17-dione
In the title compound, C20H26O2, which is the 6-methylene derivative of androstenedione and a synthetic percursor of exemestane, the steroid A ring approximates to a sofa (or envelope) conformation, with the methylene group adjacent to the link to the B ring lying out of the plane of the other atoms...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
International Union of Crystallography
2012-04-01
|
| Series: | Acta Crystallographica Section E |
| Online Access: | http://scripts.iucr.org/cgi-bin/paper?S1600536812013207 |
| id |
doaj-9339be80f928421c800b0bc8aac0fe08 |
|---|---|
| record_format |
Article |
| spelling |
doaj-9339be80f928421c800b0bc8aac0fe082020-11-24T21:22:14ZengInternational Union of CrystallographyActa Crystallographica Section E1600-53682012-04-01684o1263o126310.1107/S16005368120132076-Methylideneandrost-4-ene-3,17-dioneL. C. R. AndradeM. J. M. de AlmeidaF. M. Fernandes RoleiraC. L. VarelaE. J. Tavares da SilvaIn the title compound, C20H26O2, which is the 6-methylene derivative of androstenedione and a synthetic percursor of exemestane, the steroid A ring approximates to a sofa (or envelope) conformation, with the methylene group adjacent to the link to the B ring lying out of the plane of the other atoms. The B and C rings have slightly flattened chair conformations and the D ring is an envelope, with the CH group forming the flap. In the crystal, molecules are linked by two distinct C—H...O hydrogen bonds, involving acidic H atoms close to C=C and C=O double bonds.http://scripts.iucr.org/cgi-bin/paper?S1600536812013207 |
| collection |
DOAJ |
| language |
English |
| format |
Article |
| sources |
DOAJ |
| author |
L. C. R. Andrade M. J. M. de Almeida F. M. Fernandes Roleira C. L. Varela E. J. Tavares da Silva |
| spellingShingle |
L. C. R. Andrade M. J. M. de Almeida F. M. Fernandes Roleira C. L. Varela E. J. Tavares da Silva 6-Methylideneandrost-4-ene-3,17-dione Acta Crystallographica Section E |
| author_facet |
L. C. R. Andrade M. J. M. de Almeida F. M. Fernandes Roleira C. L. Varela E. J. Tavares da Silva |
| author_sort |
L. C. R. Andrade |
| title |
6-Methylideneandrost-4-ene-3,17-dione |
| title_short |
6-Methylideneandrost-4-ene-3,17-dione |
| title_full |
6-Methylideneandrost-4-ene-3,17-dione |
| title_fullStr |
6-Methylideneandrost-4-ene-3,17-dione |
| title_full_unstemmed |
6-Methylideneandrost-4-ene-3,17-dione |
| title_sort |
6-methylideneandrost-4-ene-3,17-dione |
| publisher |
International Union of Crystallography |
| series |
Acta Crystallographica Section E |
| issn |
1600-5368 |
| publishDate |
2012-04-01 |
| description |
In the title compound, C20H26O2, which is the 6-methylene derivative of androstenedione and a synthetic percursor of exemestane, the steroid A ring approximates to a sofa (or envelope) conformation, with the methylene group adjacent to the link to the B ring lying out of the plane of the other atoms. The B and C rings have slightly flattened chair conformations and the D ring is an envelope, with the CH group forming the flap. In the crystal, molecules are linked by two distinct C—H...O hydrogen bonds, involving acidic H atoms close to C=C and C=O double bonds. |
| url |
http://scripts.iucr.org/cgi-bin/paper?S1600536812013207 |
| work_keys_str_mv |
AT lcrandrade 6methylideneandrost4ene317dione AT mjmdealmeida 6methylideneandrost4ene317dione AT fmfernandesroleira 6methylideneandrost4ene317dione AT clvarela 6methylideneandrost4ene317dione AT ejtavaresdasilva 6methylideneandrost4ene317dione |
| _version_ |
1725996767210635264 |