The Effects of a Combination of Ion Channel Inhibitors in Female Rats Following Repeated Mild Traumatic Brain Injury

The Effects of a Combination of Ion Channel Inhibitors in Female Rats Following Repeated Mild Traumatic Brain Injury

Following mild traumatic brain injury (mTBI), the ionic homeostasis of the central nervous system (CNS) becomes imbalanced. Excess Ca<sup>2+</sup> influx into cells triggers molecular cascades, which result in detrimental effects. The authors assessed the effects of a combination of ion...

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Bibliographic Details
Main Authors: Yilin Mao, Anna M. B. Black, Hannah R. Milbourn, Samra Krakonja, Michael Nesbit, Carole A. Bartlett, Brooke Fehily, Ryu Takechi, Nathanael J. Yates, Melinda Fitzgerald
Format: Article
Language:English
Published: MDPI AG 2018-10-01
Series:International Journal of Molecular Sciences
Subjects:
neurotrauma
repeated mild traumatic brain injury
ion channel inhibitors
oxidative stress
node of Ranvier
Online Access:https://www.mdpi.com/1422-0067/19/11/3408

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