Evidence of evolutionary constraints that influences the sequence composition and diversity of mitochondrial matrix targeting signals.
Mitochondrial targeting signals (MTSs) are responsible for trafficking nuclear encoded proteins to their final destination within mitochondria. These sequences are diverse, sharing little amino acid homology and vary significantly in length, and although the formation of a positively-charged amphiph...
Main Authors: | Stephen R Doyle, Naga R P Kasinadhuni, Chee Kai Chan, Warwick N Grant |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2013-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC3692466?pdf=render |
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