Bladder cancer diagnosis and identification of clinically significant disease by combined urinary detection of Mcm5 and nuclear matrix protein 22.

Bladder cancer diagnosis and identification of clinically significant disease by combined urinary detection of Mcm5 and nuclear matrix protein 22.

Urinary biomarkers for bladder cancer detection are constrained by inadequate sensitivity or specificity. Here we evaluate the diagnostic accuracy of Mcm5, a novel cell cycle biomarker of aberrant growth, alone and in combination with NMP22.1677 consecutive patients under investigation for urinary t...

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Bibliographic Details
Main Authors: John D Kelly, Tim J Dudderidge, Alex Wollenschlaeger, Odu Okoturo, Keith Burling, Fiona Tulloch, Ian Halsall, Teresa Prevost, Andrew Toby Prevost, Joana C Vasconcelos, Wendy Robson, Hing Y Leung, Nikhil Vasdev, Robert S Pickard, Gareth H Williams, Kai Stoeber
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3392249?pdf=render

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