Dual-specificity phosphatase 6 (DUSP6): a review of its molecular characteristics and clinical relevance in cancer

Dual-specificity phosphatase 6 (DUSP6): a review of its molecular characteristics and clinical relevance in cancer

Mitogen-activated protein kinases (MAPKs) are the main regulators of cellular proliferation, growth, and survival in physiological or pathological conditions. Aberrant MAPK signaling plays a pivotal role in carcinogenesis, which leads to development and progression of human cancer. Dual-specificity...

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Bibliographic Details
Main Authors: Muhammad Khairi Ahmad, Nur Ainina Abdollah, Nurul Husna Shafie, Narazah Mohd Yusof, Siti Razila Abdul Razak
Format: Article
Language:English
Published: China Anti-Cancer Association 2018-03-01
Series:Cancer Biology & Medicine
Subjects:
Dual-specificity phosphatase 6
MAPK signaling
cancer
chemoresponsiveness
chemoresistance
Online Access:http://www.cancerbiomed.org/index.php/cocr/article/view/1087

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