Attenuation of iNOS and COX2 by blueberry polyphenols is mediated through the suppression of NF-κB activation

Attenuation of iNOS and COX2 by blueberry polyphenols is mediated through the suppression of NF-κB activation

Treatment of BV2 microglial cells with blueberry extracts has been shown to be effective in reducing lipopolysaccharide (LPS)-induced proinflammatory mediators such as nitric oxide (NO), tumor necrosis factor-alpha (TNF-α), interleukin-1 beta (IL-1β), inducible NO synthase (iNOS), and cyclooxygenase...

Full description

Bibliographic Details
Main Authors: Francis C. Lau, James A. Joseph, Jane E. McDonald, Wilhelmina Kalt
Format: Article
Language:English
Published: Elsevier 2009-07-01
Series:Journal of Functional Foods
Subjects:
Blueberries
Polyphenols
Anti-inflammation
Inducible nitric oxide synthase
Cyclooxygenase 2
Nuclear factor-kappa B
Online Access:http://www.sciencedirect.com/science/article/pii/S1756464609000334

Internet

http://www.sciencedirect.com/science/article/pii/S1756464609000334

Similar Items