Rhinovirus C targets ciliated airway epithelial cells

Abstract Background The Rhinovirus C (RV-C), first identified in 2006, produce high symptom burdens in children and asthmatics, however, their primary target host cell in the airways remains unknown. Our primary hypotheses were that RV-C target ciliated airway epithelial cells (AECs), and that cell...

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Bibliographic Details
Main Authors: Theodor F. Griggs, Yury A. Bochkov, Sarmila Basnet, Thomas R. Pasic, Rebecca A. Brockman-Schneider, Ann C. Palmenberg, James E. Gern
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Respiratory Research
Subjects:
Online Access:http://link.springer.com/article/10.1186/s12931-017-0567-0