Two Distinct E3 Ubiquitin Ligases Have Complementary Functions in the Regulation of Delta and Serrate Signaling in <italic>Drosophila</italic>

<p>Signaling by the Notch ligands Delta (Dl) and Serrate (Ser) regulates a wide variety of essential cell-fate decisions during animal development. Two distinct E3 ubiquitin ligases, Neuralized (Neur) and Mind bomb (Mib), have been shown to regulate Dl signaling in <named-content content-ty...

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Bibliographic Details
Main Authors: Le Borgne Roland, Remaud Sylvie, Hamel Sophie, Schweisguth François
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2005-01-01
Series:PLoS Biology
Subjects:
Online Access:http://dx.doi.org/10.1371/journal.pbio.0030096