Coordination of hypoxia adaptation and iron homeostasis in pathogenic fungi

In mammals, hypoxia causes facilitated erythropoiesis that requires increased iron availability with established links between oxygen and iron in regulation of the transcription factor hypoxia inducible factor (HIF). Therefore, cellular responses to hypoxia and iron starvation are linked in mammals...

Full description

Bibliographic Details
Main Authors: Dawoon eChung, Hubertus eHaas, Robert A Cramer
Format: Article
Language:English
Published: Frontiers Media S.A. 2012-11-01
Series:Frontiers in Microbiology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00381/full