Coordination of hypoxia adaptation and iron homeostasis in pathogenic fungi
In mammals, hypoxia causes facilitated erythropoiesis that requires increased iron availability with established links between oxygen and iron in regulation of the transcription factor hypoxia inducible factor (HIF). Therefore, cellular responses to hypoxia and iron starvation are linked in mammals...
Main Authors: | , , |
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Format: | Article |
Language: | English |
Published: |
Frontiers Media S.A.
2012-11-01
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Series: | Frontiers in Microbiology |
Subjects: | |
Online Access: | http://journal.frontiersin.org/Journal/10.3389/fmicb.2012.00381/full |