Role of serine racemase in behavioral sensitization in mice after repeated administration of methamphetamine.

Role of serine racemase in behavioral sensitization in mice after repeated administration of methamphetamine.

<h4>Background</h4>The N-methyl-D-aspartate (NMDA) receptors play a role in behavioral abnormalities observed after administration of the psychostimulant, methamphetamine (METH). Serine racemase (SRR) is an enzyme which synthesizes D-serine, an endogenous co-agonist of NMDA receptors. Us...

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Bibliographic Details
Main Authors: Mao Horio, Mami Kohno, Yuko Fujita, Tamaki Ishima, Ran Inoue, Hisashi Mori, Kenji Hashimoto
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/22530033/pdf/?tool=EBI

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