Very-Low-Dose Pegylated Interferon α2a Plus Ribavirin Therapy for Advanced Liver Cirrhosis Type C: A Possible Therapeutic Alternative without Splenic Intervention

Very-Low-Dose Pegylated Interferon α2a Plus Ribavirin Therapy for Advanced Liver Cirrhosis Type C: A Possible Therapeutic Alternative without Splenic Intervention

Despite the recent progress in interferon (IFN) therapies for chronic hepatitis C, liver cirrhosis remains refractory. One of the major obstacles to successful IFN therapy is low platelet count. Currently, splenic interventions, such as partial splenic embolization (PSE) or surgical splenectomy, hav...

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Bibliographic Details
Main Authors: Shogo Ohkoshi, Satoshi Yamagiwa, Masahiko Yano, Hiromichi Takahashi, Yo-hei Aoki, Yasunobu Matsuda, Yutaka Aoyagi
Format: Article
Language:English
Published: Karger Publishers 2010-07-01
Series:Case Reports in Gastroenterology
Subjects:
Low HCV titers
Liver cirrhosis type C
Low-dose pegylated interferon
Ribavirin
Low platelets
Low neutrophils
Avoiding splenic intervention
Online Access:http://www.karger.com/Article/FullText/318742

Internet

http://www.karger.com/Article/FullText/318742

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