3,4,5-Trihydroxy-N′-(1H-indol-2-ylmethylidene)benzohydrazide–1H-indole-2-carbaldehyde azine–methanol (2/1/2)

• Main Authors: Hamid Khaledi, Abeer A. Alhadi, Hapipah Mohd Ali, Ward T. Robinson, Mahmood A. Abdulla
• Format: Article
• Language: English
• Published: International Union of Crystallography 2010-01-01
• Series: Acta Crystallographica Section E
• Online Access: http://scripts.iucr.org/cgi-bin/paper?S1600536809052465
• ISSN: 1600-5368

The title compound, 2C16H13N3O4·C18H14N4·2CH4O, was crystallized from the reaction between 3,4,5-trihydroxybenzoylhydrazine and indole-2-carbaldehyde in a mixture of ethanol and methanol. The compound is a stoichiometric 2:1 cocrystal of the methanol-solvated reaction product, 3,4,5-trihydroxy-N′-(1H-indol-2-ylmethylidene)benzohydrazide and 1H-indole-2-carbaldehyde azine that arose unexpectedly during the synthesis. The former molecules are linked by O—H...O hydrogen bonds and also by π–π stacking interactions between benzoylhydrazide rings into a two-dimensional network. The methanol solvent molecules are hydrogen bonded to this network. The centrosymmetric azine molecules are not engaged in hydrogen bonding.