Case Report. The Use of Endotoxin Adsorption in Extracorporeal Blood Purification Techniques. A Case Report

Case Report. The Use of Endotoxin Adsorption in Extracorporeal Blood Purification Techniques. A Case Report

Sepsis and septic shock are major healthcare problems, resulting in high morbidity and mortality. The Surviving Sepsis Campaign (SSC), which standardised the approach to sepsis, was recently updated. Strategies to decrease the systemic inflammatory response have been proposed to modulate organ dysfu...

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Bibliographic Details
Main Authors: Hadade Adina N., Breazu Caius M., Ilie Iulian V., Mitre Calin I.
Format: Article
Language:English
Published: Sciendo 2017-04-01
Series:The Journal of Critical Care Medicine
Subjects:
endotoxin
alteco® lps adsorber
gram-negative abdominal sepsis
haemadsorption
haemodynamics
Online Access:https://doi.org/10.1515/jccm-2017-0010
Description
Summary:Sepsis and septic shock are major healthcare problems, resulting in high morbidity and mortality. The Surviving Sepsis Campaign (SSC), which standardised the approach to sepsis, was recently updated. Strategies to decrease the systemic inflammatory response have been proposed to modulate organ dysfunctions. Endotoxin, derived from the membrane of Gram-negative bacteria, is considered a major factor in the pathogenesis of sepsis. Endotoxin adsorption, if effective, has the potential to reduce the biological cascade of Gram-negative sepsis.
ISSN:2393-1817

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