Anti-epileptic effect of Ganoderma lucidum polysaccharides by inhibition of intracellular calcium accumulation and stimulation of expression of CaMKII α in epileptic hippocampal neurons.

Anti-epileptic effect of Ganoderma lucidum polysaccharides by inhibition of intracellular calcium accumulation and stimulation of expression of CaMKII α in epileptic hippocampal neurons.

<h4>Purpose</h4>To investigate the mechanism of the anti-epileptic effect of Ganoderma lucidum polysaccharides (GLP), the changes of intracellular calcium and CaMK II α expression in a model of epileptic neurons were investigated.<h4>Method</h4>Primary hippocampal neurons wer...

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Bibliographic Details
Main Authors: Shu-Qiu Wang, Xiao-Jie Li, Hong-Bin Qiu, Zhi-Mei Jiang, Maria Simon, Xiao-Ru Ma, Lei Liu, Jun-Xing Liu, Fang-Fang Wang, Yan-Feng Liang, Jia-Mei Wu, Wei-Hua Di, Shaobo Zhou
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-01-01
Series:PLoS ONE
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25010576/?tool=EBI

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/pmid/25010576/?tool=EBI

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