Membrane-type 4 matrix metalloproteinase (MT4-MMP) modulates water homeostasis in mice.

MT4-MMP is a membrane-type metalloproteinase (MMP) anchored to the membrane by a glycosyl-phosphatidylinositol (GPI) motif. GPI-type MT-MMPs (MT4- and MT6-MMP) are related to other MT-MMPs, but their physiological substrates and functions in vivo have yet to be identified. In this manuscript we show...

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Bibliographic Details
Main Authors: Manakan B Srichai, Heloisa Colleta, Leslie Gewin, Linsey Matrisian, Ty W Abel, Naohiko Koshikawa, Motoharu Seiki, Ambra Pozzi, Raymond C Harris, Roy Zent
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-02-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3037967?pdf=render

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