Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity

Forniceal deep brain stimulation induces gene expression and splicing changes that promote neurogenesis and plasticity

Clinical trials are currently underway to assess the efficacy of forniceal deep brain stimulation (DBS) for improvement of memory in Alzheimer’s patients, and forniceal DBS has been shown to improve learning and memory in a mouse model of Rett syndrome (RTT), an intellectual disability disorder caus...

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Bibliographic Details
Main Authors: Amy E Pohodich, Hari Yalamanchili, Ayush T Raman, Ying-Wooi Wan, Michael Gundry, Shuang Hao, Haijing Jin, Jianrong Tang, Zhandong Liu, Huda Y Zoghbi
Format: Article
Language:English
Published: eLife Sciences Publications Ltd 2018-03-01
Series:eLife
Subjects:
forniceal deep brain stimulation
hippocampus
neurogenesis
MeCP2
Rett syndrome
intellectual disability
Online Access:https://elifesciences.org/articles/34031

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