Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation?

Stress granules, RNA-binding proteins and polyglutamine diseases: too much aggregation?

Abstract Stress granules (SGs) are membraneless cell compartments formed in response to different stress stimuli, wherein translation factors, mRNAs, RNA-binding proteins (RBPs) and other proteins coalesce together. SGs assembly is crucial for cell survival, since SGs are implicated in the regulatio...

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Bibliographic Details
Main Authors: Adriana Marcelo, Rebekah Koppenol, Luís Pereira de Almeida, Carlos A. Matos, Clévio Nóbrega
Format: Article
Language:English
Published: Nature Publishing Group 2021-06-01
Series:Cell Death and Disease
Online Access:https://doi.org/10.1038/s41419-021-03873-8

Internet

https://doi.org/10.1038/s41419-021-03873-8

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