Fenofibrate and PBA prevent fatty acid-induced loss of adiponectin receptor and pAMPK in human hepatoma cells and in hepatitis C virus-induced steatosis

Fenofibrate and PBA prevent fatty acid-induced loss of adiponectin receptor and pAMPK in human hepatoma cells and in hepatitis C virus-induced steatosis

Adiponectin receptors play a key role in steatosis and inflammation; however, very little is known about regulation of adiponectin receptors in liver. Here, we examined the effects of palmitate loading, endoplasmic reticulum (ER) stress, and the hypolipidemic agent fenofibrate on adiponectin recepto...

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Bibliographic Details
Main Authors: Shaikh Mizanoor Rahman, Ishtiaq Qadri, Rachel C. Janssen, Jacob E. Friedman
Format: Article
Language:English
Published: Elsevier 2009-11-01
Series:Journal of Lipid Research
Subjects:
insulin resistance
inflammation
signal transduction
diabetes
obesity
palmitate
Online Access:http://www.sciencedirect.com/science/article/pii/S0022227520306854

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