Identification of H-Ras-Specific Motif for the Activation of Invasive Signaling Program in Human Breast Epithelial Cells

Increased expression and/or activation of H-Ras are often associated with tumor aggressiveness in breast cancer. Previously, we showed that H-Ras, but not N-Ras, induces MCF10A human breast epithelial cell invasion and migration, whereas both H-Ras and N-Ras induce cell proliferation and phenotypic...

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Main Authors: Hae-Young Yong, Jin-Sun Hwang, Hwajin Son, Hae-In Park, Eok-Soo Oh, Hyun-Hwi Kim, Do Kyun Kim, Wahn Soo Choi, Bong-Jin Lee, Hyeong-Reh Choi Kim, Aree Moon
Format: Article
Language:English
Published: Elsevier 2011-02-01
Series:Neoplasia: An International Journal for Oncology Research
Online Access:http://www.sciencedirect.com/science/article/pii/S1476558611800497