Measurement of technetium-99m sestamibi signals in rats administered a mitochondrial uncoupler and in a rat model of heart failure.

Measurement of technetium-99m sestamibi signals in rats administered a mitochondrial uncoupler and in a rat model of heart failure.

BACKGROUND:Many methods have been used to assess mitochondrial function. Technetium-99m sestamibi ((99m)Tc-MIBI), a lipophilic cation, is rapidly incorporated into myocardial cells by diffusion and mainly localizes to the mitochondria. The purpose of this study was to investigate whether measurement...

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Bibliographic Details
Main Authors: Akira Kawamoto, Takao Kato, Tetsuo Shioi, Junji Okuda, Tsuneaki Kawashima, Yodo Tamaki, Shinichiro Niizuma, Yohei Tanada, Genzou Takemura, Michiko Narazaki, Tetsuya Matsuda, Takeshi Kimura
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2015-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4297193?pdf=render

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